Filter Category: General

04May
Imagen blog de Linking APOA2 rs3813627 SNP to HDL and APOA1 through BMI

Linking APOA2 rs3813627 SNP to HDL and APOA1 through BMI

APOA2 is part of the apolipoprotein superfamily that includes the apolipoprotein A1 and is the second most common apolipoprotein on the human HDL.  It has been considered of minor physiological importance in lipoprotein metabolism, recent studies in rodent models have shown that APOA2 plays multiple roles in the maintenance of HDL, obesity, and obesity-related insulin resistance.

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03Feb
Imagen blog de Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/P21 and p16/Rb Pathways, and ABC Transporters

Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/P21 and p16/Rb Pathways, and ABC Transporters

Every year, about 1.5 million new breast cancer (BC) cases are diagnosed in women worldwide. This high incidence has aroused the interest of the scientific community, placing BC in the spotlight. The prevention or treatment of this chronic disease through diet is one of the most explored strategies hitherto. Resveratrol (RSV) is one of the most investigated phenolic compounds in the last decades.

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08Jan
Imagen blog de Metabolic profiling of dietary polyphenols and methylxanthines in normal and malignant mammary tissues from breast cancer patients: The POLYSEN trial

Metabolic profiling of dietary polyphenols and methylxanthines in normal and malignant mammary tissues from breast cancer patients: The POLYSEN trial

Previous studies suggest that dietary polyphenols and(or) their metabolites can exert beneficial effects against breast cancer. We usually consume in the diet, methylxanthines (caffeine, theobromine, etc.), with stimulant and cardioprotective properties, among others. However, it is unknown whether polyphenols can reach human malignant breast tumors in molecular forms and(or) at concentrations likely to act against cancer.

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19Nov
Imagen blog de RESISTANCE TRAINING AS ANTI-AGING THERAPY

RESISTANCE TRAINING AS ANTI-AGING THERAPY

Researchers from University of Oviedo have recently published a study where the importance of autophagy, a crucial process for cellular proteaostasis maintenance which decrease with age, is analyzed within the context of resistance or endurance training adaptations.

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03Oct
Imagen blog de New Study Reveals Development of Pathogenic Bacteria in Children Born by Caesarean Section

New Study Reveals Development of Pathogenic Bacteria in Children Born by Caesarean Section

A group of researchers in the United Kingdom recently published a study in which it was found that babies born by cesarean section experience changes in their microbiome with respect to babies born vaginally.

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