The group's research activity is organized around the study of the biological response to the exercise and its implications for the prescription of physical activity and on population health, becoming three lines of research: 1) circulating microRNAs as emerging biomarkers of exercise response and adaptation; 2) The effect of exercise on the maternal epigenetic legacy mediated by circulating microRNAs; 3) Ageing and lifestyle: strategies to improve cognitive reserve.
The response to acute and chronic exercise has profound effects on gene expression and involves complex cross-communication between tissues. This coordinates the systemic effects of exercise on health. Therefore, the study of the molecular response to exercise has emerged in recent years as an essential tool to understand how this response is integrated and how it relates to health status, allowing to discover, in addition, new potential mechanisms involved in disease processes, as well as new therapeutic targets. Knowing in detail the molecular response to exercise is therefore essential to optimize exercise recommendations and explore the limits of a healthy exercise.