Metabolic profiling of dietary polyphenols and methylxanthines in normal and malignant mammary tissues from breast cancer patients: The POLYSEN trial
Previous studies suggest that dietary polyphenols and(or) their metabolites can exert beneficial effects against breast cancer. We usually consume in the diet, methylxanthines (caffeine, theobromine, etc.), with stimulant and cardioprotective properties, among others. However, it is unknown whether polyphenols can reach human malignant breast tumors in molecular forms and(or) at concentrations likely to act against cancer.