Colaboradores
Laboratorio de Alimentación y Salud
Investigador/a principal: Juan Carlos Espín
Centro de investigación: Grupo de Calidad, Seguridad y Bioactividad de Alimentos Vegetales. Dep. Ciencia y Tec. Alimentos. CEBAS-CSIC (Murcia)
Teléfono: +34 968-39-6200; Ext 6344
@Food_Health_LAB
Cortés-Martín A, García-Villalba R, García-Mantrana I, Rodríguez-Varela A, Romo-Vaquero M, Collado MC, Tomás-Barberán FA, Espín JC, Selma MV. Urolithins in Human Breast Milk after Walnut Intake and Kinetics of Gordonibacter Colonization in Newly Born: The Role of Mothers' Urolithin Metabotypes.J Agric Food Chem. 2020 Nov 11;68(45):12606-12616. doi: 10.1021/acs.jafc.0c04821. Epub 2020 Nov 2.
Iglesias-Aguirre CE, Cortés-Martín A, Ávila-Gálvez MÁ, Giménez-Bastida JA, Selma MV, González-Sarrías A, Espín JC. Main drivers of (poly)phenol effects on human health: metabolite production and/or gut microbiota-associated metabotypes?Food Funct. 2021 Sep 24. doi: 10.1039/d1fo02033a.
Cortés-Martín A, Iglesias-Aguirre CE, Meoro A, Selma MV, Espín JC. Pharmacological Therapy Determines the Gut Microbiota Modulation by a Pomegranate Extract Nutraceutical in Metabolic Syndrome: A Randomized Clinical Trial. Mol Nutr Food Res. 2021 Mar;65(6):e2001048. doi: 10.1002/mnfr.202001048. Epub 2021 Feb 11.
Giménez-Bastida JA, González-Sarrías A, Laparra-Llopis JM, Schneider C, Espín JC. Targeting Mammalian 5-Lipoxygenase by Dietary Phenolics as an Anti-Inflammatory Mechanism: A Systematic Review. Int J Mol Sci. 2021 Jul 25;22(15):7937. doi: 10.3390/ijms22157937.
Barber C, Mego M, Sabater C, Vallejo F, Bendezu RA, Masihy M, Guarner F, Espín JC, Margolles A, Azpiroz F. Differential Effects of Western and Mediterranean-Type Diets on Gut Microbiota: A Metagenomics and Metabolomics Approach. Nutrients. 2021 Jul 30;13(8):2638. doi: 10.3390/nu13082638.
Ávila-Gálvez MÁ, Giménez-Bastida JA, González-Sarrías A, Espín JC. New Insights into the Metabolism of the Flavanones Eriocitrin and Hesperidin: A Comparative Human Pharmacokinetic Study. Antioxidants (Basel). 2021 Mar 11;10(3):435. doi: 10.3390/antiox10030435.
Ávila-Gálvez MÁ, González-Sarrías A, Martínez-Díaz F, Abellán B, Martínez-Torrano AJ, Fernández-López AJ, Giménez-Bastida JA, Espín JC. Disposition of Dietary Polyphenols in Breast Cancer Patients' Tumors, and Their Associated Anticancer Activity: The Particular Case of Curcumin. Mol Nutr Food Res. 2021 Jun;65(12):e2100163. doi: 10.1002/mnfr.202100163. Epub 2021 May 10.
González-Sarrías, A.; García-Villalba, R.; Romo-Vaquero, M.; Alasalvar, C.; Örem, A.; Zafrilla, P.; Tomás-Barberán, F.A.; Selma, M.V.; Espín, J.C. Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight-obese individuals consuming pomegranate: A randomised clinical trial. Mol. Nutr. Food Res. 61: 5, 1600830; Doi: 10.1002/mnfr.201600830
Espín, J.C.; González-Sarrías, A.; Tomás-Barberán, F.A. (2017). The gut microbiota: a key factor in the therapeutic effects of (poly)phenols. Biochem. Pharmacol. 139:82-93
Selma, M.V.; González-Sarrías, A.; Salas-Salvadó, J.; Andrés-Lacueva, C.; Alasalvar, C.; Örem, A.; Tomás-Barberán, F.A.; Espín, J.C. (2018). The gut microbiota metabolism of pomegranate or walnut ellagitannins yields two urolithin-metabotypes that correlate with cardiometabolic risk biomarkers: comparison between normoweight, overweight-obesity and metabolic syndrome. Clin. Nutr. 37, 897-905.
Cortés-Martín, A.; García-Villalba, R.; González-Sarrías, A.; Romo-Vaquero, M.; Loria-Kohen, V.; Ramírez-de-Molina, V.; Tomás-Barberán, F.A.; Selma, M.V.; Espín, J.C. (2018). The gut microbiota urolithin metabotypes revisited: The human metabolism of ellagic acid is mainly determined by ageing. Food & Funct. 9, 4100-4106.
Romo-Vaquero, M.; Cortés-Martín, A.; Loria-Kohen, V.; Ramírez-de-Molina, A.; García-Mantrana, I.; Collado, M.C.; Espín, J.C.; Selma, M.V. (2019). Deciphering the human gut microbiome of urolithin metabotypes: association with enterotypes and potential cardiometabolic health implications. Mol. Nutr. Food Res. 2018, 63, e1800958. doi: 10.1002/mnfr.201800958.
Ávila-Gálvez, M.A.; García-Villalba, R.; Martínez-Díaz, F.; Ocaña-Castillo, B.; Monedero-Saiz, T.; Torrecillas-Sánchez, A.; Abellán, B.; González-Sarrías, A.; Espín, J.C. (2019). Metabolic profiling of dietary polyphenols and methylxanthines in normal and malignant mammary tissues from breast cancer patients. Mol Nutr. Food Res. e1801239. doi: 10.1002/mnfr.201801239.
- González-Sarrías, A.; García-Villalba, R.; Romo-Vaquero, M.; Alasalvar, C.; Örem, A.; Zafrilla, P.; Tomás-Barberán, F.A.; Selma, M.V.; Espín, J.C. Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight-obese individuals consuming pomegranate: A randomised clinical trial. Mol. Nutr. Food Res. 61: 5, 1600830; Doi: 10.1002/mnfr.201600830
- Espín, J.C.; González-Sarrías, A.; Tomás-Barberán, F.A. (2017). The gut microbiota: a key factor in the therapeutic effects of (poly)phenols. Biochem. Pharmacol. 139:82-93
- Selma, M.V.; González-Sarrías, A.; Salas-Salvadó, J.; Andrés-Lacueva, C.; Alasalvar, C.; Örem, A.; Tomás-Barberán, F.A.; Espín, J.C. (2018). The gut microbiota metabolism of pomegranate or walnut ellagitannins yields two urolithin-metabotypes that correlate with cardiometabolic risk biomarkers: comparison between normoweight, overweight-obesity and metabolic syndrome. Clin. Nutr. 37, 897-905.
- Cortés-Martín, A.; García-Villalba, R.; González-Sarrías, A.; Romo-Vaquero, M.; Loria-Kohen, V.; Ramírez-de-Molina, V.; Tomás-Barberán, F.A.; Selma, M.V.; Espín, J.C. (2018). The gut microbiota urolithin metabotypes revisited: The human metabolism of ellagic acid is mainly determined by ageing. Food & Funct. 9, 4100-4106.
- Romo-Vaquero, M.; Cortés-Martín, A.; Loria-Kohen, V.; Ramírez-de-Molina, A.; García-Mantrana, I.; Collado, M.C.; Espín, J.C.; Selma, M.V. (2019). Deciphering the human gut microbiome of urolithin metabotypes: association with enterotypes and potential cardiometabolic health implications. Mol. Nutr. Food Res. 2018, 63, e1800958. doi: 10.1002/mnfr.201800958.
- Ávila-Gálvez, M.A.; García-Villalba, R.; Martínez-Díaz, F.; Ocaña-Castillo, B.; Monedero-Saiz, T.; Torrecillas-Sánchez, A.; Abellán, B.; González-Sarrías, A.; Espín, J.C. (2019). Metabolic profiling of dietary polyphenols and methylxanthines in normal and malignant mammary tissues from breast cancer patients. Mol Nutr. Food Res. e1801239. doi: 10.1002/mnfr.201801239.